Evaluation of flavonoid fraction of trigonella foenumgraecum for its wound healing potential

Theerthahalli, Arun Sudheendra and Shenoy, Rekha and Taranalli, Ashok D (2009) Evaluation of flavonoid fraction of trigonella foenumgraecum for its wound healing potential. Pharmacologyonline, 1. pp. 1154-1162.

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Abstract

Wound healing potential of Trigonella foenum- graecum (TFG) was evaluated in the present study. The study was done on rodents using incision, excision and dead space wound models. The flavonoid fraction of TFG seed enhanced the breaking strength of incision wounds significantly at 200mg/kg and 500mg/kg (p< 0.01) as compared to control. At both the dose levels, TFG fraction showed significant reduction in the wound area in the excision wound model. Dry granuloma weight and granuloma tissue breaking strength were increased significantly by TFG. Histopathological reports of the granulation tissue of the treated groups showed better healing when compared to control. These results indicated the pro-healing effect of flavonoid fraction of TFG seed.

Item Type: Article
Uncontrolled Keywords: Trigonella foenum-graecum, wound, tensile strength, excision model, granuloma, Hydroxyproline
Subjects: Pharmacy > MCOPS Manipal > Pharmacology
Depositing User: KMC Manipal
Date Deposited: 12 Jul 2011 10:34
Last Modified: 18 Oct 2013 05:21
URI: http://eprints.manipal.edu/id/eprint/550

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