Curcumin inhibits nitrite-induced methemoglobin formation.

Unnikrishnan, MK and Rao, MNA (1992) Curcumin inhibits nitrite-induced methemoglobin formation. FEBS Letters, 301 (2). pp. 195-196.

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Abstract

Curcumin protects hemoglobin from nitrite-induced oxidation to methemoglobin. The protection is not observed when curcumin is added after the autocatalytic stage of the oxidation of hemoglobin by nitrite. The ability of curcumin to scavenge superoxide may be responsible since superoxide is implicated in promoting the autocatalytic stage of oxidation of hemoglobin by nitrite.

Item Type: Article
Uncontrolled Keywords: Curcumin, Methomoglobin formation inhibition, Nitrite-induced methomoglobin, Antioxidant.
Subjects: Pharmacy > MCOPS Manipal > Pharmaceutical Chemistry
Depositing User: KMC Manipal
Date Deposited: 12 Jul 2011 10:22
Last Modified: 12 Jul 2011 10:22
URI: http://eprints.manipal.edu/id/eprint/557

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