Effective drug targeting by Erythrocytes as Carrier Systems

Gopal, VS and Kumar, Ranjith A and Usha, AN and Karthik, A and Udupa, N (2007) Effective drug targeting by Erythrocytes as Carrier Systems. Current Trends in Biotechnology and Pharmacy, 1 (1). pp. 18-33. ISSN 0973 - 8916

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Carrier erythrocytes, resealed erythrocytes loaded by a drug or other therapeutic agents, have been exploited extensively in recent years for both temporally and spatially controlled delivery of a wide variety of drugs and other bioactive agents owing to their remarkable degree of biocompatibility, biodegradability and a series of other potential advantages. Biopharmaceuticals, therapeutically significant peptides and proteins, nucleic acid-based biologicals, antigens and vaccines, are among the recently focused pharmaceuticals for being delivered using carrier erythrocytes. In this article, the potential applications of erythrocytes in drug delivery have been reviewed with a particular stress on the studies and laboratory experiences on successful erythrocyte loading and characterization of the different classes of drugs.

Item Type: Article
Uncontrolled Keywords: Erythrocyte, Carrier erythrocytes, Cellular carriers, Resealed erythrocytes, Carrier RBCs.
Subjects: Pharmacy > MCOPS Manipal > Pharmaceutics
Depositing User: KMC Manipal
Date Deposited: 27 Apr 2012 06:49
Last Modified: 27 Apr 2012 06:49
URI: http://eprints.manipal.edu/id/eprint/76345

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