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Gammagluatamyl trans peptidase and total cholesterol levels in smokers and congestive cardiac failure patients.

*, Sreekantha and *, Vinod Chandran and *, Amareshwara M and *, Avinash SS and *, Remya and *, Kodliwadmath.MV (2012) Gammagluatamyl trans peptidase and total cholesterol levels in smokers and congestive cardiac failure patients. Indian journal of public health research and development , 3 (2). pp. 165-167.

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Abstract

Background and Objectives: The level of gamma glutamyl transpeptidase (GGTP or GGT) is especially increased in alcoholic liver diseases with biliary obstruction. There are many other diseases where alterations in the level of GGTP are noted. Hence, the study was aimed to estimate the level of GGTP in smokers and congestive cardiac failure (CCF) patients along with total cholesterol (TC). Materials and Methods: 35 each clinically diagnosed CCF patients, smokers and normal healthy male subjects were included in the study. GGTP was estimated by enzymatic colorimetric method and total cholesterol by cholesterol oxidase peroxidase method using P-800 chemistry antoanalyser. Statistical analysis was done using ANOVA. Results: The GGTP and TC levels were significantly (p<0.001) increased in the both CCF patients and smokers but increase is more significant in CCF patients. Conclusion: GGTP can be used as a potential biomarker along with total cholesterol in cardiovascular diseases especially CCF because of their direct relationship with the indication of atherogenesis

Item Type: Article
Uncontrolled Keywords: GGTP, TC, CCF, Smokers
Subjects: Medicine > KMC Mangalore > Biochemistry
Depositing User: KMCMLR User
Date Deposited: 17 May 2012 10:49
Last Modified: 17 May 2012 10:49
URI: http://eprints.manipal.edu/id/eprint/76430

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