Henoch–Schonlein purpura: An update

Kamath, Nutan and Rao, Suchetha (2012) Henoch–Schonlein purpura: An update. Indian Journal of Rheumatology, 7 (1). pp. 92-98.

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Abstract

Henoch–Schonlein purpura (HSP), the commonest childhood vasculitis, is characterised by non-thrombocytopaenic palpable purpura, arthritis or arthralgias, gastrointestinal and renal involvement. The peak incidence is between the ages of 4 years and 8 years with a male preponderance. Though the diagnosis is usually clinical, a tissue biopsy revealing leucocytoclastic vasculitis is helpful when the presentation is atypical. Renal involvement in the form of an immune complex glomerulonephritis is the most serious long-term complication. The aetiopathogenesis, classification, clinical features, relevant Indian data, and a stepwise management approach with corticosteroids and immunosuppressive agents per the renal histology are discussed.

Item Type: Article
Additional Information: Suppl
Uncontrolled Keywords: Arthritis, children, nephritis, palpable purpura, vasculitis
Subjects: Medicine > KMC Mangalore > Paediatrics
Depositing User: KMCMLR User
Date Deposited: 28 Jun 2012 05:15
Last Modified: 28 Jun 2012 05:15
URI: http://eprints.manipal.edu/id/eprint/76766

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