Effect of Exercise-Based Cardiac Rehabilitation on Ejection Fraction in Coronary Artery Disease Patients: A Randomized Controlled Trial

Haddadzadeh, Mohammad H and Maiya, Arun G and Padmakumar, R (2011) Effect of Exercise-Based Cardiac Rehabilitation on Ejection Fraction in Coronary Artery Disease Patients: A Randomized Controlled Trial. Heart Views, 12 (2). pp. 51-57.

[img] PDF
HeartViews_2011_12_2_51_86013[1].pdf - Published Version
Restricted to Registered users only

Download (1MB) | Request a copy

Abstract

Background: Exercise training as a part of cardiac rehabilitation aims to restore patient with heart disease to health. However, left ventricular ejection fraction (LVEF) is clinically used as a predictor of long-term prognosis in coronary artery disease (CAD) patients, there is a scarcity of data on the effectiveness of exercise-based cardiac rehabilitation on LVEF. Objective: To investigate the effectiveness of exercise-based cardiac rehabilitation on LVEF in early post-event CAD patients. Patients and Methods: In a single blinded, randomized controlled trial, post-coronary event CAD patients from the age group of 35–75 years, surgically (Coronary artery bypass graft or percutaneous coronary angioplasty) or conservatively treated, were recruited from Golsar Hospital, Iran. Exclusion criteria were high-risk group (AACVPR-99) patients and contraindications to exercise testing and training. Forty-two patients were randomized either into Study or Control. The study group underwent a 12-week structured individually tailored exercise program either in the form of Center-based (CExs) or Home-based (HExs) according to the ACSM-2005 guidelines. The control group only received the usual cardiac care without any exercise training. LVEF was measured before and after 12 weeks of exercise training for all three groups. Differences between and within groups were analyzed using the general linear model, two-way repeated measures at alfa=0.05. Results: Mean age of the subjects was 60.5 ± 8.9 years. There was a significant increase in LVEF in the study (46.9 ± 5.9 to 61.5 ± 5.3) group compared with the control (47.9 ± 7.0 to 47.6 ± 6.9) group (P=0.001). There was no significant difference in changes in LVEF between the HExs and CExs groups (P=1.0). Conclusion: A 12-week early (within 1 month post-discharge) structured individually tailored exercise training could significantly improve LVEF in post-event CAD patients.

Item Type: Article
Uncontrolled Keywords: Cardiac rehabilitation, coronary artery disease, ejection fraction, exercise training
Subjects: Allied Health > MCOAHS Manipal > Physiotherapy
Medicine > KMC Manipal > Cardiology
Depositing User: KMC Manipal
Date Deposited: 11 Jul 2012 04:50
Last Modified: 11 Jul 2012 04:50
URI: http://eprints.manipal.edu/id/eprint/76813

Actions (login required)

View Item View Item