Effects of metformin use in pregnant patients with polycystic ovary syndrome

Kumar, Pratap and Khan, Kashif (2012) Effects of metformin use in pregnant patients with polycystic ovary syndrome. Journal of Human Reproductive Sciences, 5 (2). pp. 166-169.

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Abstract

Use of metformin throughout pregnancy in women with polycystic ovary syndrome (PCOS) has shown to reduce the rates of early pregnancy loss, preterm labor, and prevention of fetal growth restriction. Metformin has been shown to have encouraging effects on several metabolic aspects of polycystic ovarian syndrome, such as insulin sensitivity, plasma glucose concentration and lipid profile and since women with PCOS are more likely than healthy women to suffer from pregnancy-related problems like early pregnancy loss, gestational diabetes mellitus and hypertensive states in pregnancy, the use of metformin therapy in these patients throughout pregnancy may have beneficial effects on early pregnancy loss and development of gestational diabetes.

Item Type: Article
Uncontrolled Keywords: Metformin, PCOS, Pregnancy
Subjects: Medicine > KMC Manipal > Obstetrics & Gynaecology
Depositing User: KMC Manipal
Date Deposited: 18 Sep 2012 11:29
Last Modified: 18 Sep 2012 11:29
URI: http://eprints.manipal.edu/id/eprint/77243

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