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Bacteriology of neonatal septicaemia

Bhat , S and *, Kavitha and Rao , S (2011) Bacteriology of neonatal septicaemia. International Journal of Scientific and Research Publications, 1 (1). pp. 18-21. ISSN 2250-3056

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Abstract

Background: Septicaemia is one of the important causes of mortality and morbidity in neonates. Blood culture is the gold standard for its diagnosis. Emergence of multidrug resistant bacterial strains is a major problem in the management of neonatal sepsis. Present study was undertaken to identify the common bacterial pathogens associated with neonatal sepsis and to determine their antibiotic susceptibility pattern. Materials and Methods: Blood cultures from 125 suspected cases of neonatal sepsis were examined. The growths from the sub-cultures were identified by conventional biochemical tests. Antibiotic susceptibility testing was performed by Modified Kirby-Bauer disc diffusion method and drug resistant strains in primary screening were further processed for ESBL and MRSA status by combination disc method (ESBL) and Oxacillin disc diffusion method (MRSA). Results: Out of the 125 cultures obtained from suspected cases, 57(45.6%) were culture positive. 35.08% of the culture isolates were Gram negative bacilli. 63.15% of the isolates were Gram positive cocci. The prevalence of MRSA in 26 strains of Staphylococcus aureus was found to be 23.07% (6 strains). The overall prevalence of ESBL producers among Gram negative bacterial isolates was 35% (7 strains). Conclusion: This study stresses the need for the continuous screening and surveillance for antibiotic resistance in NICU.

Item Type: Article
Uncontrolled Keywords: neonatal sepsis, MRSA, ESBL, blood culture
Subjects: Medicine > KMC Mangalore > Microbiology
Depositing User: KMCMLR User
Date Deposited: 25 Sep 2012 10:19
Last Modified: 25 Sep 2012 10:19
URI: http://eprints.manipal.edu/id/eprint/77275

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