Superbug NDM-1: A global health problem

Suthar, Sharad Kumar and Joseph, Alex and Lohan, Sandeep and Alex, Angel Treasa (2012) Superbug NDM-1: A global health problem. Der Pharmacia Lettre, 4 (4). pp. 1183-1187. ISSN 0975-5071

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Abstract

The worldwide emergence of NDM-1 positive, multiresistant Enterobacteriacae have created a major global health problem. The NDM-1 can catalyze the hydrolysis of a various antibiotics including the latest generation carbapenems, which are often referred as the last line of antibiotics active against multiresistant gram-negative pathogens. Also there are few antiobiotics in pipeline active against gram-negative microbes and none that are active against NDM-1; presents a serious threat to antibiotics therapy. We are suggesting a rational use of antibiotics with an implementation of stringent policy for the prescription of antibiotics especially in the developing countries where antibiotics abuse is more common. The World Health Organization should also issue a guideline pertaining to NDM-1 positive, multiresistant Enerobacteriacae.

Item Type: Article
Uncontrolled Keywords: New Delhi metallo-β-lactamase-1; gram-negative pathogens; resistant; carbapenems.
Subjects: Pharmacy > MCOPS Manipal > Pharmaceutical Biotechnology
Pharmacy > MCOPS Manipal > Pharmaceutical Chemistry
Depositing User: KMC Manipal
Date Deposited: 18 Oct 2012 10:54
Last Modified: 18 Oct 2012 10:54
URI: http://eprints.manipal.edu/id/eprint/77465

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