Kumar, Naveen and Kumar, Pramod and Prasad, Keerthana and Nayak, Satheesha B (2012) A histological study on the distribution of dermal collagen and elastic fibres in different regions of the body. International Journal of Medicine and Medical Sciences, 4 (8). pp. 171-176. ISSN 2006-9723

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Abstract

The aim of the study was to assess the unequal distributions of dermal collagen and elastic content in skin sections perpendicular to each other from different regions of the body. We collected 20 skin samples from 10 regions of a cadaver. From each region, 2 samples were collected in 2 directions which were perpendicular to each other. Histological slides were prepared and stained for collagen and elastic fibres’. Photomicrographs taken from special stained sections were analysed using simple and reliable software “tissue quant” method. Various ratios were calculated. The quantitative fraction in terms of percentage area occupied by collagen and elastic fibres were observed to be different in different regions as well as in different directions of sections taken. This unequal distribution of the dermal collagen and elastic fibres in 2 different directions of the sections will possibly have an effect on wound healing process which in turn may have an effect on varied scar appearance and behaviour based on the region and direction of wound.

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