Synthesis and biological activities of some fused benzopyrimidine-4-ones

Vachala, Seekarajapuram Dinakaraan and Keloth, Kaitheri Srinivasan (2012) Synthesis and biological activities of some fused benzopyrimidine-4-ones. Indian Journal of Heterocyclic Chemistry, 21. pp. 189-192.

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Condensation of anthranilic acid with acid chloride afforded 2-substituted benzoic acids which on cyclization with different primary amines yielded sthe corresponding 2,3- disubstituted quinazolin 4-(3H)-ones (B1-B6). The structure of the synthesized compounds was confirmed by spectral studies. All these compounds were screened for their antiinflammatory and antimicrobial activities by rat paw edema model and min inhibitory concentration determination methods respectively

Item Type: Article
Subjects: Pharmacy > MCOPS Manipal > Pharmaceutical Chemistry
Depositing User: KMC Manipal
Date Deposited: 26 Nov 2012 04:17
Last Modified: 26 Nov 2012 04:17

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