Synthesis, characterisation, antioxidant and anticancer evaluation of novel schiff’s bases of 2-quinolones

Jayashree, BS and Kaur, Manpreet and Pai, Aravinda (2012) Synthesis, characterisation, antioxidant and anticancer evaluation of novel schiff’s bases of 2-quinolones. Elixir Online Journal, 52. pp. 11317-11322.

[img] PDF
52_(2012)_11317-11322.pdf - Published Version
Restricted to Registered users only

Download (608kB) | Request a copy

Abstract

A series of novel Schiff’s bases of 2-Quinolones have been synthesized using Coumarin 4 aldehydes and different substituted amines as starting materials under conventional heating method and were obtained in good yields. The synthesized compounds were screened for their anti-oxidant activity by DPPH· method and were also tested for their antiproliferative activity against Lung cancer cell lines by MTT assay method. The details of the present work is presented here

Item Type: Article
Uncontrolled Keywords: 2-quinolones, Schiff’s bases, Anticancer activity, MTT assay method
Subjects: Pharmacy > MCOPS Manipal > Pharmaceutical Chemistry
Depositing User: KMC Manipal
Date Deposited: 10 Dec 2012 06:16
Last Modified: 10 Dec 2012 06:16
URI: http://eprints.manipal.edu/id/eprint/77666

Actions (login required)

View Item View Item