Effects of procoagulants on wound healing

Ramesh, KV and Rao, Mallikarjuna C and Bairy, KL and Ramanarayan, K and Kulkarni, DR (1990) Effects of procoagulants on wound healing. Indian Journal of Experimental Biology, 28. pp. 43-45.

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Abstract

As blood coagulation is a prelude for wound healing, a systemic haemocoagulant (Botropase) and local procoagulants (thrombin and fibrin) were evaluated on physical (wound breaking strength, wound half-closure time and period of epithelization), biochemical (granuloma-hydroxyproline and hexosamine) and histological attributes of healing wounds in albino rats. Botropase prompted all phases of tissue repair. Thrombin delayed wound contraction whereas fibrin had no discernable action. The findings that proco~gulants modify healing process has bearing on their surg;cal use.

Item Type: Article
Subjects: Medicine > KMC Manipal > Pathology
Pharmacy > MCOPS Manipal > Pharmacology
Depositing User: KMC Manipal
Date Deposited: 03 Jan 2013 05:57
Last Modified: 24 Dec 2013 06:40
URI: http://eprints.manipal.edu/id/eprint/77816

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