Amyloid Goiter: A case of primary thyroid amyloid disease

Pai, Kanthilatha and Ramachandra, L and Susmitha, MS and Suresh, BP (2010) Amyloid Goiter: A case of primary thyroid amyloid disease. The Internet Journal of Surgery, 22 (2). pp. 1-4.

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Abstract

Amyloid goiter can be defined as the presence of amyloid within the thyroid gland in such quantities as to produce a clinically apparent enlargement of the gland.It is a rare disease which occurs in association with both primary and secondary amyloidosis. Focal microscopic deposits of amyloid substance may often be found within the thyroid gland in association with systemic (generalized) amyloidosis, medullary carcinoma, and, less frequently, primary amyloidosis of the thyroid (1). It is a rare entity and should be suspected in patients who are known to have diseases predisposing to amyloid deposition. This condition has to be distinguished from other types of goitre and malignancy. Inspite of extensive involvement, patients are usually euthyroid and diagnosis is established on histopathological evaluation. Surgical intervention is necessary to relieve the symptoms of neck mass and establish a diagnosis. The diagnosis of amyloid goitre should be suspected in patients with a diffusely enlarging thyroid gland and in those with an appropriate clinical history

Item Type: Article
Uncontrolled Keywords: Amyloidosis / Thyroid / Primary
Subjects: Medicine > KMC Manipal > Pathology
Medicine > KMC Manipal > Surgery
Depositing User: KMC Manipal
Date Deposited: 06 Feb 2013 06:40
Last Modified: 06 Feb 2013 06:40
URI: http://eprints.manipal.edu/id/eprint/78190

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