Sacrococcygeal myxopapillary ependymoma with anaplastic ependymoma component in an infant

Chakraborti, Shrijeet and Kini, Hema and Pai, Ganesh K and Upadhyaya, Vidya (2012) Sacrococcygeal myxopapillary ependymoma with anaplastic ependymoma component in an infant. Journal of Pediatric Neurosciences, 7 (3). pp. 218-220. ISSN 1817-1745

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Sacrococcygeal location of myxopapillary ependymoma (MPE) is uncommon. Local recurrence and metastases are on record inspite of its benign characteristics. We report a rare case of sacrococcygeal MPE in an 11‑month‑old female child who showed typical myxopapillary ependymal histology along with anaplastic ependymal component. Ki‑67 labeling index in the myxopapillary component was 4‑5% and in the anaplastic component was 70%. Six weeks after gross total resection of the tumor, the child presented with local recurrence and metastasis in the right inguinal lymph nodes and was treated with chemotherapy. The present case of sacrococcygeal MPE with anaplastic ependymoma component is the second case on record in the medical literature, and the first case without any syndromic features. Metastasis in this case can be explained because of the anaplastic component, with mitotic count of 5‑6/high power field and high Ki‑67 labeling index.

Item Type: Article
Uncontrolled Keywords: Anaplastic ependymoma, Ki‑67, myxopapillary ependymoma, sacrococcyx
Subjects: Medicine > KMC Mangalore > Pathology
Medicine > KMC Mangalore > Surgery
Depositing User: KMCMLR User
Date Deposited: 16 Feb 2013 06:18
Last Modified: 16 Feb 2013 06:18

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