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Effect of maleic acid and ethylenediaminetetraacetic acid on the dissolution of human pulp tissue –an in vitro study

Ballal, N. V. and *, Kundabala M and Bhat , K. S. (2011) Effect of maleic acid and ethylenediaminetetraacetic acid on the dissolution of human pulp tissue –an in vitro study. International Endodontic Journal , 44. pp. 353-356.

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Abstract

Aim To compare in vitro, the tissue-dissolution capacity of7%maleic acid (MA), 17%ethylenediaminetetraacetic acid (EDTA), 2.5% sodium hypochlorite (NaOCl) (positive control) and 0.9% saline (NaCl) (negative control) on human pulp tissue. Methodology Forty pieces of human pulp tissue, each weighing 0.026 g, were divided randomly into four groups (n = 10): (i) 7% MA solution, (ii) 17% EDTA solution, (iii) 2.5% NaOCl solution and (iv) 0.9% NaCl solution. The pulp tissue was placed in beakers ontaining the test solutions and then placed on a vibrator. Pulp tissue from the four experimental solutions was blotted dry and weighed after 30, 60, 90 and 120 min. The percentage of weight loss was calculated, and the data were statistically analysed using Kruskal– Wallis and Mann–Whitney U-test. Results At all time intervals, 2.5% NaOCl dissolved pulp tissue significantly more than the other solutions (P < 0.001). There was no significant difference in the pulp-dissolution capacity between 7% MA and 17% EDTA at any of the time intervals. NaCl (0.9%) did not have any effect on pulp tissue. Conclusion Seven percentage of MA and 17% EDTA had minimal tissue-dissolution capacity when compared to NaOCl.

Item Type: Article
Uncontrolled Keywords: ethylenediaminetetraacetic acid, maleic acid, pulp dissolution, sodium hypochlorite
Subjects: Dentistry > MCODS Mangalore > Conservative Dentistry
Depositing User: KMCMLR User
Date Deposited: 19 Feb 2013 11:23
Last Modified: 28 Apr 2014 07:22
URI: http://eprints.manipal.edu/id/eprint/78557

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