Rai, Padmalatha S (2012) Anti- Inflammatory Properties of Aegle Marmelos Extracts by Carageenan Induced Rat Paw Edema In Rats. International Journal of Universal Pharmacy and Life Sciences, 2 (3). pp. 648-655. ISSN 2249-6793

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Abstract

In the present study A. marmelos selected for evaluation of antiinflammatory properties in rats. The anti-inflammatory activity of A. marmelos is screened by adopting carrageenan induced paw edema model and the degree of paw edema was measured by using Plethysometer. The petroleum ether and ethanol extract of leaf of A. marmelos significantly inhibited the development of edema. Administration of oral suspensions of petroleum ether and ethanol extract of leaf of A. marmelos significantly inhibited the development of edema from the 60 minutes to 180 minutes in petroleum ether extract of leaf and from 30 minutes to 180 minutes in ethanol extract of leaf after giving carrageenan injection. The standard drug diclofenac sodium was also exhibited much higher inhibition of edema formation at 180 minutes. The aqueous extract of leaf, petroleum ether, ethanol and aqueous extract of stem and petroleum ether, ethanol, aqueous extract of root failed to exhibit anti-inflammatory activity.

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