Applications of ‘TissueQuant’– A color intensity Quantification tool for Medical research

Prasad, Keerthana and kumar , Bhagath P and Chakravarthy, Marx and Prabhu, G K (2012) Applications of ‘TissueQuant’– A color intensity Quantification tool for Medical research. Computer Methods and Programs in Biomedicine, 106 (1). pp. 27-36.

[img] PDF
CMPB-TissueQuant_-_full_article.pdf - Published Version
Restricted to Registered users only

Download (1MB) | Request a copy
Official URL:


This paper demonstrates the use of TissueQuant – an image analysis tool for quantification of color intensities which was developed for use in medical research where the stained biological specimen such as tissue or antigen needs to be quantified. TissueQuant provides facilities for user interaction to choose and quantify the color of interest and its shades. Gaussian weighting functions are used to provide a color score which quantifies how close the shade is to the user specified reference color. We describe two studies in medical research which use TissueQuant for quantification. The first study evaluated the effect of petroleum- ether extract of Cissus quadrangularis (CQ) on osteoporotic rats. It was found that the analysis results correlated well with the manual evaluation, p < 0.001. The second study evaluated the nerve morphometry and it was found that the adipose and non adipose tissue content was maximum in radial nerve among the five nerves studied.

Item Type: Article
Additional Information: © 2011 Elsevier Ireland Ltd. All rights reserved.
Uncontrolled Keywords: Image analysis; Automation; Color analysis; Medical research
Subjects: Medicine > KMC Manipal > Anatomy
Engineering > MIT Manipal > Biomedical
Information Sciences > MCIS Manipal
Depositing User: MIT Library
Date Deposited: 22 Feb 2013 11:17
Last Modified: 22 Feb 2013 11:17

Actions (login required)

View Item View Item