Radioprotective effect of Phyllanthus niruri on mouse chromosomes

Rao, Satish BS (2000) Radioprotective effect of Phyllanthus niruri on mouse chromosomes. CURRENT SCIENCE, 78 (10). pp. 1245-1247.

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Micronuclei (MN) induction in the mouse bone marrow polychromatic erythrocytes (PCE) and normochromatic erythrocytes (NCE) was studied 24 h after whole body exposure to 4 Gy of gamma radiation with or without a single intraperitoneal injection of 25 mg/kg to 150 mg/kg of 50% methanolic extract of Phyllanthus niruri (whole aerial part). The extract significantly reduced the radiationinduced MN induction in both PCE and NCE and increased the ratio of PCE to NCE. The effect increased linearly with extract dose from 25 to 125 mg/kg.

Item Type: Article
Subjects: Life Sciences > MLSC Manipal
Depositing User: KMC Manipal
Date Deposited: 27 Feb 2013 10:56
Last Modified: 27 Feb 2013 10:56

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