Mundkur, Suneel C and Swaminathan, N and Lewis, Leslie (2011) A Possibile role of Antenatal Vitamin K Administration in Preventing Epiphyseal Stippling in Fetal Hydantoin Syndrome. WebmedCentral, 2 (12). pp. 1-4. ISSN 2046-1690

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Abstract

The effect of conventional anti-convulsant, Phenytoin, on bone health is described in the literature. There is increasing evidence on the role of Vitamin K in bone health and in prevention of osteoporotic fractures (4) We report a case of a newborn with fetal hydantoin syndrome associated with epiphyseal stippling and consider a possible protective role of antenatal administration of vitamin K to mothers on phenytoin to prevent vitamin K induced epiphyseal stippling in the neonate.

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