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In-vitro alpha-glucosidase inhibitory activity of abraga chendhooram, a Siddha drug

Amuthan, Arul (2012) In-vitro alpha-glucosidase inhibitory activity of abraga chendhooram, a Siddha drug. International Journal of Pharmacology and Clinical Sciences, 1 (3). pp. 79-81.

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Abstract

The present study was carried out to evaluate alpha-glucosidase inhibitory activity of abraga chendhooram which is a Siddha drug being used to treat diabetes mellitus. The ingredient of abraga chendhooram includes biotite (K(Mg,Fe)3AlSi3O10(F,OH)2), Sesbania grandiflora, Calotropis gigantea and Momordica charantia. In-vitro alpha-glucosidase inhibitory assay was performed by standard procedure. Different concentrations of abraga chendhooram and miglitol (standard drug) were used. Abraga chendhooram exhibited a dose dependent alpha-glucosidase inhibitory activity, but it was less than standard drug. Further studies are warranted to look other possible mechanisms for its antidiabetic claim and to assess its safety

Item Type: Article
Uncontrolled Keywords: Ayurveda, diabetes mellitus, herbo-metallic, biotite, abraga, mica, basma
Subjects: Medicine > MMMC Manipal > Pharmacology
Depositing User: KMC Manipal
Date Deposited: 25 Mar 2013 06:10
Last Modified: 25 Mar 2013 06:10
URI: http://eprints.manipal.edu/id/eprint/79256

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