Fibrin-ring granulomas in Scrub typhus: An unrecognized entity

Khanna, Ruchee and Nayak, Deepak M and Chethan, Manohar and Belurkar, Sushma V and Akshatha, N (2013) Fibrin-ring granulomas in Scrub typhus: An unrecognized entity. International Journal of Scientific and Research Publications, 3 (2). pp. 1-3. ISSN 2250-3153

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Fibrin-ring granuloma (FRG) is characterized by a ring of fibrin and epithelioid histiocytes arranged around a central fat vacuole. It is classically described in Q fever. We report a case of FRG in the bone marrow biopsy of a 45-year old male with pancytopenia and clinical features of sepsis and bleeding diathesis. Serologically, the antibodies against Orientia tsutsugamushi were positive; being diagnostic of scrub typhus. The patient responded to specific antibiotics and supportive treatment. Thus, scrub typhus should be included as aetiology for FRG.

Item Type: Article
Uncontrolled Keywords: Fibrin-ring granuloma (FRG); Scrub typhus;Bone marrow biopsy, Sepsis
Subjects: Medicine > MMMC Manipal > Pathology
Medicine > KMC Manipal > Pathology
Depositing User: KMC Manipal
Date Deposited: 25 Mar 2013 06:32
Last Modified: 25 Mar 2013 06:32

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