Pure Erythroleukemia: A Case Report And Literature Review

Khanna, Ruchee and Nayak, Deepak M and Manohar, Chethan and Seshadri, Shubha and Belurkar, Sushma V (2011) Pure Erythroleukemia: A Case Report And Literature Review. The Internet Journal of Hematology, 7 (2).

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Abstract

Pure erythroleukemia is a rare hematopoietic neoplasm, seldom reported in literature. Varied reports suggest a prevalence of 3-5% of all AML. We report one such case, presenting with non classical symptoms in a 65 year old lady. Peripheral smear examination and complete hemogram revealed a pancytopenic profile with circulating basophilic erythroblasts. Bone marrow study yielded erythroid hyperplasia with abundance of PAS positive proerythroblasts and dyspoiesis in other lineages. Pure erythroleukemias are known to carry a poor response to standard chemotherapy. The present case is a testament not only to the rarity of the disease but also for a reminder that such an aggressive neoplasm can indeed present in the most inconspicuous manner.

Item Type: Article
Uncontrolled Keywords: Pure erythroleukemia, erythroleukemia, 6Ma, 6Mb, proerythroblasts, glycophorin A, WHO classification, FAB subtype B, pancytopenia, CD36, CD117
Subjects: Medicine > KMC Manipal > Medicine
Medicine > KMC Manipal > Pathology
Depositing User: KMC Manipal
Date Deposited: 27 Mar 2013 07:01
Last Modified: 27 Mar 2013 07:01
URI: http://eprints.manipal.edu/id/eprint/79315

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