Morphometric evaluation of endometrial blood vessels

Makhija, Divya and Mathai, Alka Mary and Naik, Ramadas and Kumar, Suneet and Rai, Sharada and Pai, Muktha R and Baliga, Poornima (2008) Morphometric evaluation of endometrial blood vessels. Indian Journal of Pathology & Microbiology, 51 (3). pp. 346-350.

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Five hundred endometrial specimens were studied to document the changes in blood vessels in various phases of menstrual cycle, menstrual disturbances and in unexplained infertility. Sixty-three cases were taken as control and 437 cases as study group which included cases of dysfunctional uterine bleeding (DUB), endometrial polyps, fibroids, adenomyosis, infertility and atrophic endometrium. Using light microscopy, the vascular morphology was studied. The blood vessels were concentrated more in basal layer in the proliferative phase and in functional layer in the secretory phase. Cases of complex hyperplasia and pill endometrium had significantly higher vessel concentration. Congestion and dilatation of blood vessels were significantly higher in cases of DUB. The present study showed a positive correlation between endometrial angiogenesis and menstrual disorders. The alteration in blood vessel morphology has significant role in prognosis and in various anti-angiogenic therapies.

Item Type: Article
Uncontrolled Keywords: Blood vessels, dysfunctional uterine bleeding, endometrium
Subjects: Medicine > KMC Manipal > Pathology
Depositing User: KMC Manipal
Date Deposited: 28 Mar 2013 04:46
Last Modified: 28 Mar 2013 04:46

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