Anti-arthritic Activity of the Plant Tinospora Cordifolia Willd

Paval, Jaijesh and Kaitheri, Srinivasan Keloth and Govindan, Sreejith and Mohammed, Ciraj Ali and Kumar, Raju Suresh and Narayanan, Sareesh Naduvil and Maloor, Prasad Alathady (2011) Anti-arthritic Activity of the Plant Tinospora Cordifolia Willd. Journal of Herbal Medicine and Toxicology, 5 (1). pp. 11-16. ISSN 0973-4643

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Abstract

Tinospora cordifolia Willd. (Menispermaceae) has been used in Indian and Chinese traditional medicines against various ailments. To demonstrate the antiarthritic activity of ethanol extract of Tinospora cordifolia arthritis was induced in Wistar rats using Freund’s complete adjuvant and Bovine type II collagen. We used various haematological parameters to assess the effectiveness of the treatment. These were supported by histological study of the affected ankle joints using haematoxylin and eosin. Results suggested that oral dosage of 150 mg/kg body weight exhibited anti-arthritic activity in Freund’s adjuvants arthritic rats. In collagen induced arthritic rats, the dosage of 100 mg/kg body weight showed anti-arthritic activity. We conclude that the Tinospora cordifolia demonstrates a significant anti-arthritic activity

Item Type: Article
Uncontrolled Keywords: Arthritis; Inflammation; Freund’s complete djuvant; Collagen, Paw volume
Subjects: Medicine > MMMC Manipal > Anatomy
Medicine > MMMC Manipal > Microbiology
Medicine > MMMC Manipal > Physiology
Pharmacy > MCOPS Manipal > Pharmaceutical Chemistry
Depositing User: KMC Manipal
Date Deposited: 05 Apr 2013 11:30
Last Modified: 05 Apr 2013 11:30
URI: http://eprints.manipal.edu/id/eprint/79496

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