Kudva, Ranjini and Perveen, Shahin and Janardhana, Aithala (2010) Primary epithelioid angiosarcoma of bone: A case report with immunohistochemical study. Indian Journal of Pathology and Microbiology, 53 (4). pp. 811-813.

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Abstract

Primary malignant vascular tumors of the bone are exceedingly rare and represent <1% of primary malignant bone tumors. Angiosarcoma is a malignant mesenchymal neoplasm in which the neoplastic cells demonstrate endothelial differentiation. Epithelioid angiosarcoma (EA) is a rare variant of angiosarcoma that is characterized by large cells with an epithelioid morphology. EA is an aggressive tumor with poor prognosis. Here, we present a case of a 62-year-old man who had primary EA of the left tibia. He was treated with amputation and chemotherapy. After 1 month of chemotherapy, he developed pleural effusion and died.

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