Microwave-assisted synthesis and evaluation of N-substituted thiazolidine-2,4-dione derivatives as antimicrobial agents

Gaonkar, Santosh L and Namratha, B and Shetty, Nitinkumar S and Shimizu, Hiroki (2014) Microwave-assisted synthesis and evaluation of N-substituted thiazolidine-2,4-dione derivatives as antimicrobial agents. Interactive Medicinal Chemistry. ISSN 2053-7107

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Abstract

A series of N-substituted thiazolidine-2,4-dione derivatives bearing potentially bioactive substituents were synthesized by microwave irradiation method. Structural elucidation was accomplished by 1H NMR, 13C NMR, IR, Mass and elemental analyses. The synthesized compounds were evaluated for antimicrobial activities. Among the compounds studied, compounds 4i and 4d showed potent antimicrobial activities.

Item Type: Article
Uncontrolled Keywords: Thiazolidine-2,4-dione, antimicrobial activities, microwave irradiation, N-substituted thiazolidine-2,4-dione
Subjects: Engineering > MIT Manipal > Chemistry
Depositing User: MIT Library
Date Deposited: 02 Jun 2014 06:02
Last Modified: 02 Jun 2014 06:02
URI: http://eprints.manipal.edu/id/eprint/139570

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