Synthesis and Crystal Structure of 4-[2-(Methyl-pyridin2-ylamino)ethoxy]- benzaldoxime

Prasad, Mahadeva T N and Gaonkar, Santosh L and Kapoor, Kamini and Gupta, Vivek K and Rajnikant, . and Shimizu, Hiroki and Sridhar, MA and Prasad, Shashidhara J (2012) Synthesis and Crystal Structure of 4-[2-(Methyl-pyridin2-ylamino)ethoxy]- benzaldoxime. X-ray Structure Analysis Online, 28. pp. 25-26.

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Abstract

Functionalized nitrogen-heterocyclesplay apredominantrole inmedicinal chemistry. Pyridine derivatives represent a peculiar class of antiviral compounds that qualify as promising novel drugs for exploration as potential anti-HIV agents.1 Pyridine derivatives are used in the treatment of alzheimer’s decease,2 and mycobacterium tuberculosis H37Rv,3 and as agonists atr 5- HT1a receptors.4 The pyridine nucleus is prevalent in numerous natural products, and is extremely important in the chemistry of biological systems.5 The title compound, 4-[2-(methyl-pyridin- 2-ylamino)ethoxy]benzaldoxime, is a very useful intermediate for the synthesis of many biologically active isoxazolines and isoxazoles.

Item Type: Article
Subjects: Engineering > MIT Manipal > Chemistry
Depositing User: MIT Library
Date Deposited: 21 Jun 2014 11:20
Last Modified: 21 Jun 2014 11:20
URI: http://eprints.manipal.edu/id/eprint/139881

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