Effect of Novel Chalcone Derivatives on Clinical Isolates of Multidrug Resistant Bacterial Strains

Maiya, Mallika and Akshatha, SJ and Shenoy, Vivekananda and Shobha, KL and Bhat, Subrahmanya K (2015) Effect of Novel Chalcone Derivatives on Clinical Isolates of Multidrug Resistant Bacterial Strains. Research Journal of Pharmaceutical, Biological and Chemical Sciences, 6 (2). pp. 466-470. ISSN 0975-8585

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Abstract

We synthesized and studied the efficacy of hydroxy and corresponding tosyloxy chalcone derivatives to inhibit the growth of MDR strains of bacteria. The required compounds were synthesized using literature methods and characterized by spectroscopic techniques. Bacterial strains were isolated by clinical methods. Our studies show hydroxy chalcone derivative is effective in inhibiting the growth of MDR bacterial strains whereas tosyl derivative is inactive.

Item Type: Article
Uncontrolled Keywords: Chalcone, hydroxy chalcones; tosyloxy chalcone; MDR strains
Subjects: Engineering > MIT Manipal > Chemistry
Depositing User: MIT Library
Date Deposited: 14 Mar 2015 11:47
Last Modified: 14 Mar 2015 11:47
URI: http://eprints.manipal.edu/id/eprint/142173

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