Evaluation of in vitro antioxidant activity of ethanol extract of Carmona retusa (Vahl.) Masam

Chandrappa, C P and Govindappa, M and Kumar, Anil N V and Channabasava, . and Chandrasekar, N and Umashankar, T (2013) Evaluation of in vitro antioxidant activity of ethanol extract of Carmona retusa (Vahl.) Masam. International Journal of Scientific & Engineering Research, 4 (12). pp. 861-876. ISSN 2229-5518

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Abstract

Oxidants contribute to more than one hundred disorders in humans. The ethanol extract of Carmona retusa was screened for antioxidant activity using 1,1-Diphenyl-2-Picryl Hydroxyl (DPPH) scavenging, Ferric Reducing Antioxidant Power (FRAP), hydrogen peroxide scavenging capacity (H2O2), reducing power assay and determination of the total antioxidant capacity by phosphomolybdenum method. The ethanol extract exhibited maximum antioxidant activity in DPPH, hydrogen peroxide. The reducing power and FRAP increased with increasing concentration of the sample. The scavenging activity of Carmona retusa found maximum in the DPPH, FRAP, hydrogen peroxide scavenging and reducing power assay of 95.35%, 9.296%, 78.539% and 82.9% respectively at 400μg/mL concentration with IC50 values of 93.35, 3.36, 12.62 and 20.79 μg/ml respectively. Percentage of antioxidant capacity with respect to one gram of dried plant extract in phosphomolybdenum method was found to be 8.875. The antioxidant activity of the sample was comparable with that of the standard ascorbic acid. This is the primary and preliminary work in Carmona retusa.

Item Type: Article
Uncontrolled Keywords: Carmona retusa, Antioxidant, DPPH, FRAP, Reducing power
Subjects: Engineering > MIT Manipal > Chemistry
Depositing User: MIT Library
Date Deposited: 21 Dec 2015 10:24
Last Modified: 21 Dec 2015 10:24
URI: http://eprints.manipal.edu/id/eprint/144892

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