Facile one-pot multicomponent synthesis of 1H-pyrazolo[3,4-b]quinolines using L-proline as a catalyst

Hegde, Hemanth and Shetty, Nitinkumar S (2017) Facile one-pot multicomponent synthesis of 1H-pyrazolo[3,4-b]quinolines using L-proline as a catalyst. Chemistry of Heterocyclic Compounds, 53 (8). pp. 883-886. ISSN 0009-3122

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Abstract

An efficient protocol for the synthesis of a new series of 1H-pyrazolo[3,4-b]quinolines has been described. The target compounds have been synthesized by one-pot multicomponent reaction of aniline, aromatic aldehydes, and 5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol- 3-one using L-proline as an organocatalyst. Structural diversity and high yields of products, broad scope of aromatic aldehydes, simple operation, and short reaction times have been demonstrated as the advantages of the developed synthetic approach.

Item Type: Article
Uncontrolled Keywords: L-proline, 1H-pyrazolo[3,4-b]quinolines, multicomponent reaction, one-pot synthesis, organocatalyst.
Subjects: Engineering > MIT Manipal > Chemistry
Depositing User: MIT Library
Date Deposited: 29 Nov 2017 05:58
Last Modified: 29 Nov 2017 05:58
URI: http://eprints.manipal.edu/id/eprint/150089

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