Effect of pre-donation fluid intake on fluid shift from interstitial tointravascular compartment in blood donors

Chenna, Deepika and Shastry, Shamee (2018) Effect of pre-donation fluid intake on fluid shift from interstitial tointravascular compartment in blood donors. Transfusion and Apheresis Science, 57 (1). pp. 54-57. ISSN 1473-0502

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Background: Fluid shifts from interstitial to intravascular space during blood donation helps in compen-sating the lost blood volume. We aimed to determine the volume of fluid shift following donation indonors with and without pre-donation fluid intake.Methods: We studied the fluid shift in 325 blood donors prospectively. Donors were divided in groups-with no fluid intake (GI) and either water (GII) or oral rehydrating fluids (GIII) before donation. Fluidshift following donation was calculated based on the difference between the pre and post donation bloodvolume. The influence of oral fluid intake, age, gender and body mass index (BMI) on volume of fluid shiftwas analyzed.Results: The fluid shift was significant between donors without fluids (GI: 127 ± 81 ml) and donors withfluid intake (GII & III: 96 ± 45 ml) (p < 0.05). The difference was not significant between donors with waterintake (GII: 106 ± 52 ml) and oral rehydrating fluid intake (GIII: 87 ± 41 ml). The shifted fluid volumeincreased with increasing BMI and decreased with increasing age in females. The fluid shift increased infemales than in males.Conclusion: The age, gender, BMI and VVR did not significantly contribute to the volume of fluid shift fol-lowing donation. As per our observation, the oral fluids before donation might not contribute to increasein fluid shift in blood donors after donation.

Item Type: Article
Uncontrolled Keywords: Fluid shift; blood donors; blood donation; donor reactions; interstitial fluida.
Subjects: Medicine > KMC Manipal > Immunohematology and Blood Transfusion
Depositing User: KMC Library
Date Deposited: 28 May 2018 04:09
Last Modified: 28 May 2018 04:09
URI: http://eprints.manipal.edu/id/eprint/151155

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