Protein-based gels: preparation,characterizations, applications in drug delivery, and tissue engineering

Thakur, Goutam and Rodrigues, Fiona C and Dathathri, Eshwari and Nayak, Suraj K (2018) Protein-based gels: preparation,characterizations, applications in drug delivery, and tissue engineering. In: Polymeric GelsCharacterization, Properties and Biomedical Applications. Woodhead Publishing, Elsevier.

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Gels are defined as cross-linked three-dimensional (3-D) structures consisting of two components, namely, structuring materials, and solvent phase. These structuring materials can be either organic or inorganic molecules and may either be crosslinked by physical or chemical interactions (Sahiner et al., 2006). The interactions among these structuring materials are responsible for the formation of the gel network. Interest in the protein biopolymers for fabricating gels has increased over the recent years. These biopolymers have favorable properties, such as water solubility, biocompatibility, nontoxicity, and sustainability making them hold immense potential for applications in drug delivery and tissue engineering (Jiang et al., 2014). These structuring agents are usually derived from natural sources such as plant and animal origins. Because the protein and the peptides are readily available, they are inexpensive and often preferred over synthetic polymers. This chapter provides an in-depth review on the different protein-based gels including hydrogels, microgels, and nanogels. This entry also provides insight into the applications of the proteins such as collagen, gelatin, elastin, and silk proteins in drug delivery and tissue engineering.

Item Type: Book Section
Subjects: Engineering > MIT Manipal > Biotechnology
Depositing User: MIT Library
Date Deposited: 30 Nov 2018 05:35
Last Modified: 30 Nov 2018 05:35

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