Correlation between basal metabolic rate, visceral fat and insulin resistance among type 2 diabetes mellitus with peripheral neuropath

Kumar, Sampath A and Maiya, Arun G and Shastry, BA and Vaishali, K and Maiya, Shubha and Umakanth, Shashikiran (2018) Correlation between basal metabolic rate, visceral fat and insulin resistance among type 2 diabetes mellitus with peripheral neuropath. Diabetes & Metabolic Syndrome: Clinical Research & Reviews, 13. pp. 344-348. ISSN 1871-4021

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Background: Basal Metabolic Rate (BMR) means the amount of energy utilized by body in physical and psychological resting rate, after a night sleep, awake without any previous physical activity post meal (10 h after last meal) & neutral environment. In people with type 2 diabetes mellitus (T2DM) there is an increase in BMR which is said to be associated with the level of glycaemic control. So, the objective of the study was to find out the correlation between BMR, Insulin resistance and Visceral fat in T2DM with peripheral neuropathy.Materials & methods: A total of 50 participants with T2DM with peripheral neuropathy were included.Age group of 30e75 years were selected for the study. Participants with a known history of neurological disease, locomotor disability, and pregnancy were excluded from the study. Demographic details of the participants like duration of diabetes mellitus, age, Fasting Blood Glucose, Fasting Insulin, HOMA-IR, Glycated Haemoglobin (HBA1c), Neuropathy and Blood pressure values were noted. We measured Basal Metabolic Rate (BMR) by using Mifflin-St Jeor predictive equation in T2DM with peripheral neuropathy.Results: The mean age of the participants is 60.16 ± 10.62. The mean duration of T2DM 13.44 ± 11.92. In the present study we found a statistical significant correlation between BMR and HOMA IR (r ¼ 0.913*;p ¼ 0.000), BMR & Fasting blood sugar (FBS) (r ¼ 0.281*; p ¼ 0.048), BMR and Visceral fat (VF) (r ¼ 0.332*; p ¼ 0.018).Conclusion: Basal metabolic rate is correlated to Homa-IR, visceral fat, fasting blood sugar and musculoskeletal mass among T2DM with peripheral neuropathy.

Item Type: Article
Uncontrolled Keywords: Basal energy expenditure; Insulin resistance; Type 2 diabetes mellitus; Peripheral neuropathy; Predictive equation; Bioelectrical impedance analysis
Subjects: Allied Health > MCOAHS Manipal > Physiotherapy
Medicine > KMC Manipal > Medicine
Depositing User: KMC Library
Date Deposited: 01 Jan 2019 10:38
Last Modified: 01 Jan 2019 10:38

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